| 来源类型 | Working Paper |
| 规范类型 | 报告 |
| DOI | 10.3386/w26500 |
| 来源ID | Working Paper 26500 |
| Origins of the Opioid Crisis and Its Enduring Impacts | |
| Abby E. Alpert; William N. Evans; Ethan M.J. Lieber; David Powell | |
| 发表日期 | 2019-12-02 |
| 出版年 | 2019 |
| 语种 | 英语 |
| 摘要 | Overdose deaths involving opioids have increased dramatically since the mid-1990s, leading to the worst drug overdose epidemic in U.S. history, but there is limited empirical evidence on the initial causes. In this paper, we examine the role of the 1996 introduction and marketing of OxyContin as a potential leading cause of the opioid crisis. We leverage cross-state variation in exposure to OxyContin’s introduction due to a state policy that substantially limited OxyContin’s early entry and marketing in select states. Recently-unsealed court documents involving Purdue Pharma show that state-based triplicate prescription programs posed a major obstacle to sales of OxyContin and suggest that less marketing was targeted to states with these programs. We find that OxyContin distribution was about 50% lower in “triplicate states” in the years after the launch. While triplicate states had higher rates of overdose deaths prior to 1996, this relationship flipped shortly after the launch and triplicate states saw substantially slower growth in overdose deaths, continuing even twenty years after OxyContin's introduction. Our results show that the introduction and marketing of OxyContin explain a substantial share of overdose deaths over the last two decades. |
| 主题 | Health, Education, and Welfare ; Health |
| URL | https://www.nber.org/papers/w26500 |
| 来源智库 | National Bureau of Economic Research (United States) |
| 引用统计 | |
| 资源类型 | 智库出版物 |
| 条目标识符 | http://119.78.100.153/handle/2XGU8XDN/584173 |
| 推荐引用方式 GB/T 7714 | Abby E. Alpert,William N. Evans,Ethan M.J. Lieber,et al. Origins of the Opioid Crisis and Its Enduring Impacts. 2019. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 资源类型 | 版本类型 | 开放类型 | 使用许可 | ||
| w26500.pdf（1547KB） | 智库出版物 | 限制开放 | CC BY-NC-SA | 浏览 | ||
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