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This brief summarizes findings from a random assignment impact study of an adapted version of the Reducing the Risk teen pregnancy prevention curriculum in rural Kentucky. Although rural counties have the highest teen birth rates in the United States, teen pregnancy prevention practitioners and researchers have developed and tested relatively few programs for youth in rural areas. To add to the research on effective pregnancy prevention approaches for youth in rural areas, the Administration for Children and Families within the U.S. Department of Health and Human Services funded a rigorous evaluation of an adapted, eight-hour version of Reducing the Risk in 13 high schools in a primarily rural area of central and southwestern Kentucky. The program was delivered by trained staff from two local health departments in Kentucky with federal grant funding from the Personal Responsibility Education Program (PREP).