G2TT
来源类型Monograph (IIASA Interim Report)
规范类型报告
Epidemic dynamics of a vector-borne disease on a village-and-city star network with commuters.
Mpolya EA; Yashima K; Ohtsuki H; Sasaki A
发表日期2013
出版者IIASA, Laxenburg, Austria: IR-13-053
出版年2013
语种英语
摘要We develop a star-network of connections between a central city and peripheral villages and analyze the epidemic dynamics of a vector-borne disease as influenced by daily commuters. We obtain an analytical solution for the global basic reproductive number R0 and investigate its dependence on key parameters for disease control. We find that in a star-network topology the central hub is not always the best place to focus disease intervention strategies. Disease control decisions are sensitive to the number of commuters from villages to the city as well as the relative densities of mosquitoes between villages and city. With more commuters it becomes important to focus on the surrounding villages. Commuting to the city paradoxically reduces the disease burden even when the bulk of infections are in the city because of the resulting diluting effects of transmissions with more commuters. This effect decreases with heterogeneity in host and vector population sizes in the villages due to the formation of peripheral epicenters of infection. We suggest that to ensure effective control of vector-borne diseases in star networks of villages and cities it is also important to focus on the commuters and where they come from.
主题Evolution and Ecology (EEP)
关键词Epidemiology Vector-borne disease Frequency-dependent transmission Star network Basic reproductive number
URLhttp://pure.iiasa.ac.at/id/eprint/10713/
来源智库International Institute for Applied Systems Analysis (Austria)
资源类型智库出版物
条目标识符http://119.78.100.153/handle/2XGU8XDN/125939
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Mpolya EA,Yashima K,Ohtsuki H,et al. Epidemic dynamics of a vector-borne disease on a village-and-city star network with commuters.. 2013.
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